Maternal choline supplementation programs greater activity of the phosphatidylethanolamine N-methyltransferase (PEMT) pathway in adult Ts65Dn trisomic mice

Maternal choline supplementation (MCS) induces lifelong cognitive benefits in the Ts65Dn mouse, a trisomic mouse model of Down syndrome and Alzheimer's disease. To gain insight into the mechanisms underlying these beneficial effects, we conducted a study to test the hypothesis that MCS alters c...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Yan, Jian, Ginsberg, Stephen D., Powers, Brian, Alldred, Melissa J., Saltzman, Arthur, Strupp, Barbara J., Caudill, Marie A.
פורמט: Artigo
שפה:Inglês
יצא לאור: Federation of American Societies for Experimental Biology 2014
נושאים:
Research Communications
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202107/
https://ncbi.nlm.nih.gov/pubmed/24963152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-251736
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