Effects of Maternal Choline Supplementation on the Septohippocampal Cholinergic System in the Ts65Dn Mouse Model of Down Syndrome

Down syndrome (DS), caused by trisomy of chromosome 21, is marked by intellectual disability (ID) and early onset of Alzheimer’s disease (AD) neuropathology including hippocampal cholinergic projection system degeneration. Here we determined the effects of age and maternal choline supplementation (M...

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Publicado no:Curr Alzheimer Res
Main Authors: Kelley, Christy M., Ash, Jessica A., Powers, Brian E., Velazquez, Ramon, Alldred, Melissa J., Ikonomovic, Milos D., Ginsberg, Stephen D., Strupp, Barbara J., Mufson, Elliott J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733527/
https://ncbi.nlm.nih.gov/pubmed/26391045
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