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Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications

Mitochondrial dysfunction in adipose tissue occurs in obesity, type 2 diabetes, and some forms of lipodystrophy, but whether this dysfunction contributes to or is the result of these disorders is unknown. To investigate the physiological consequences of severe mitochondrial impairment in adipose tis...

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Detalhes bibliográficos
Main Authors: Vernochet, Cecile, Damilano, Federico, Mourier, Arnaud, Bezy, Olivier, Mori, Marcelo A., Smyth, Graham, Rosenzweig, Anthony, Larsson, Nils-Göran, Kahn, C. Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202105/
https://ncbi.nlm.nih.gov/pubmed/25005176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-253971
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