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Effective innate and adaptive anti-melanoma immunity through localized TLR-7/8 activation
Intratumoral immune activation can induce local and systemic anti-tumor immunity. Imiquimod is a cream-formulated, TLR-7 agonist that is FDA-approved for the treatment of non-melanoma skin cancers, but has limited activity against melanoma. We studied the anti-tumor activity and mechanism of action...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4201984/ https://ncbi.nlm.nih.gov/pubmed/25252955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401160 |
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