Peptide vaccine formulation controls the duration of antigen presentation and magnitude of tumor-specific CD8+ T cell response

Despite remarkable progresses in vaccinology, therapeutic cancer vaccines have not achieved their full potential. We previously showed that an excessively long duration of antigen presentation critically reduced the quantity and quality of vaccination-induced T cell responses and subsequent anti-tum...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Khong, Hiep, Volmari, Annika, Sharma, Meenu, Dai, Zhimin, Imo, Chinonye S., Hailemichael, Yared, Singh, Manisha, Moore, Derek T., Xiao, Zhilan, Huang, Xue-fei, Horvath, Thomas D., Hawke, David H., Overwijk., Willem W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940548/
https://ncbi.nlm.nih.gov/pubmed/29643190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700467
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