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Progression of relapsing-remitting demyelinating disease does not require increased TCR affinity or epitope spread
In this study, we investigate the basis of T cell recognition of myelin that governs the progression from acute symptoms into disease remission, relapse and chronic progression in a secondary progressive model of demyelinating disease. Until now, the frequency and affinity of myelin-reactive CD4 T c...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4201951/ https://ncbi.nlm.nih.gov/pubmed/25267971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401456 |
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