Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation

INTRODUCTION: Circulating histones have been identified as mediators of damage in animal models of sepsis and in patients with trauma-associated lung injury. Despite existing controversies on actual histone concentrations, clinical implications and mechanism of action in various disease conditions,...

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Main Authors: Ekaney, Michael Liembo, Otto, Gordon Philipp, Sossdorf, Maik, Sponholz, Christoph, Boehringer, Michael, Loesche, Wolfgang, Rittirsch, Daniel, Wilharm, Arne, Kurzai, Oliver, Bauer, Michael, Claus, Ralf Alexander
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201918/
https://ncbi.nlm.nih.gov/pubmed/25260379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-014-0543-8
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