An empirically derived composite cognitive test score with improved power to track and evaluate treatments for preclinical Alzheimer’s disease

BACKGROUND: There is growing interest in the evaluation of preclinical Alzheimer’s disease (AD) treatments. As a result, there is a need to identify a cognitive composite that is sensitive to tracking preclinical AD decline to be used as a primary endpoint in treatment trials. METHODS: Longitudinal...

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Detalhes bibliográficos
Main Authors: Langbaum, Jessica B.S., Hendrix, Suzanne B., Ayutyanont, Napatkamon, Chen, Kewei, Fleisher, Adam S., Shah, Raj C., Barnes, Lisa L., Bennett, David A., Tariot, Pierre N., Reiman, Eric M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201904/
https://ncbi.nlm.nih.gov/pubmed/24751827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2014.02.002
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