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Complement Protein C1q and Adiponectin Stimulate Mer Tyrosine Kinase-Dependent Engulfment of Apoptotic Cells through a Shared Pathway

The failure to clear apoptotic cells is linked to defects in development and autoimmunity. Complement component C1q is required for efficient engulfment of apoptotic cells (efferocytosis), and C1q deficiency leads to the development of lupus. We recently identified a novel molecular mechanism for C1...

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Autors principals: Galvan, Manuel D., Hulsebus, Holly, Heitker, Thomas, Zeng, Erliang, Bohlson, Suzanne S.
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201872/
https://ncbi.nlm.nih.gov/pubmed/24942043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000363295
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