Cystic Fibrosis Sputum DNA Has NETosis Characteristics and Neutrophil Extracellular Trap Release Is Regulated by Macrophage Migration-Inhibitory Factor

Neutrophils are the main proinflammatory cell type in chronically infected lungs of cystic fibrosis (CF) patients; however, they fail to effectively clear the colonizing pathogens. Here, we investigated the molecular composition of non-mucoid and mucoid Pseudomonas aeruginosa-induced neutrophil extr...

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Autors principals: Dwyer, Markryan, Shan, Qiang, D'Ortona, Samantha, Maurer, Rie, Mitchell, Robert, Olesen, Hanne, Thiel, Steffen, Huebner, Johannes, Gadjeva, Mihaela
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2014
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201867/
https://ncbi.nlm.nih.gov/pubmed/24862346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000363242
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