Homotrimeric Macrophage Migration Inhibitory Factor (MIF) Drives Inflammatory Responses in the Corneal Epithelium by Promoting Caveolin-rich Platform Assembly in Response to Infection

Acute inflammation that arises during Pseudomonas aeruginosa-induced ocular infection can trigger tissue damage resulting in long term impairment of visual function, suggesting that the appropriate treatment strategy should include the use of anti-inflammatory agents in addition to antibiotics. We r...

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Bibliographic Details
Main Authors: Reidy, Thomas, Rittenberg, Alexander, Dwyer, Markryan, D'Ortona, Samantha, Pier, Gerald, Gadjeva, Mihaela
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605645/
https://ncbi.nlm.nih.gov/pubmed/23372160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.351064
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