CC-1065 and the duocarmycins: unraveling the keys to a new class of naturally derived DNA alkylating agents.

Ítems similars

• Rational Design, Synthesis, and Evaluation of Key Analogues of CC-1065 and the Duocarmycins
  per: Tichenor, Mark S., et al.
  Publicat: (2007)
• A unique class of duocarmycin and CC-1065 analogues subject to reductive activation
  per: Jin, Wei, et al.
  Publicat: (2007)
• Fundamental Relationships Between Structure, Reactivity, and Biological Activity for the Duocarmycins and CC-1065
  per: MacMillan, Karen S., et al.
  Publicat: (2009)
• Demonstration of a pronounced effect of noncovalent binding selectivity on the (+)-CC-1065 DNA alkylation and identification of the pharmacophore of the alkylation subunit.
  per: Boger, D L, et al.
  Publicat: (1991)
• Determination of the Biological Activity and Structure Activity Relationships of Drugs Based on the Highly Cytotoxic Duocarmycins and CC-1065
  per: Tietze, Lutz F., et al.
  Publicat: (2009)