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Ral small GTPase signaling and oncogenesis: more than just 15 minutes of fame
Since their discovery in 1986, Ral (Ras-like) GTPases have emerged as critical regulators of diverse cellular functions. Ral-selective guanine nucleotide exchange factors (RalGEFs) function as downstream effectors of the Ras oncoprotein, and the RalGEF-Ral signaling network comprises the third best...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4201770/ https://ncbi.nlm.nih.gov/pubmed/25219551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.09.004 |
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