PARAMETRIC IMAGING AND TEST-RETEST VARIABILITY OF (11)C-(+)-PHNO BINDING TO D(2)/D(3) DOPAMINE RECEPTORS IN HUMANS ON THE HRRT PET SCANNER

(11)C-(+)-PHNO is an agonist radioligand for imaging dopamine D(2) and D(3) receptors in the human brain with PET. In this study we evaluated the reproducibility of (11)C-(+)-PHNO binding parameters using a within-day design and assessed parametric imaging methods. METHODS: Repeated studies were per...

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Huvudupphovsmän: Gallezot, Jean-Dominique, Zheng, Ming-Qiang, Lim, Keunpoong, Lin, Shu-fei, Labaree, David, Matuskey, David, Huang, Yiyun, Ding, Yu-Shin, Carson, Richard E., Malison, Robert T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201637/
https://ncbi.nlm.nih.gov/pubmed/24732151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.113.132928
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