Mismatch repair status and BRAF mutation status in metastatic colorectal cancer patients: a pooled analysis of the CAIRO, CAIRO2, COIN and FOCUS studies

PURPOSE: To determine the prevalence and prognostic value of mismatch repair (MMR) status and its relation to BRAF mutation (BRAF(MT)) status in metastatic colorectal cancer (mCRC). EXPERIMENTAL DESIGN: A pooled analysis of four phase III studies in first-line treatment of mCRC (CAIRO, CAIRO2, COIN...

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Detalhes bibliográficos
Main Authors: Venderbosch, Sabine, Nagtegaal, Iris D., Maughan, Tim S., Smith, Christopher G., Cheadle, Jeremy P., Fisher, David, Kaplan, Richard, Quirke, Philip, Seymour, Matthew T., Richman, Susan D., Meijer, Gerrit A., Ylstra, Bauke, Heideman, Danielle A.M., de Haan, Anton F.J., Punt, Cornelis J.A., Koopman, Miriam
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201568/
https://ncbi.nlm.nih.gov/pubmed/25139339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0332
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