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Oxygen-sensitive calcium channels in vascular smooth muscle and their possible role in hypoxic arterial relaxation.

We have investigated the modifications of cytosolic [Ca2+] and the activity of Ca2+ channels in freshly dispersed arterial myocytes to test whether lowering O2 tension (PO2) directly influences Ca2+ homeostasis in these cells. Unclamped cells loaded with fura-2 AM exhibit oscillations of cytosolic C...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Franco-Obregón, A, Ureña, J, López-Barneo, J
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1995
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42015/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7753871/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.10.4715
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