RhoB Differentially Controls Akt Function in Tumor Cells and Stromal Endothelial Cells during Breast Tumorigenesis

Tumors are composed of cancer cells but also a larger number of diverse stromal cells in the tumor microenvironment. Stromal cells provide essential supports to tumor pathophysiology but the distinct characteristics of their signaling networks are not usually considered in developing drugs to target...

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Autori principali: Kazerounian, Shiva, Gerald, Damien, Huang, Minzhou, Chin, Y. Rebecca, Udayakumar, Durga, Zheng, Ningning, O'Donnell, Rebekah K., Perruzzi, Carole, Mangiante, Lee, Pourat, Jacob, Phung, Thuy L., Bravo-Nuevo, Arturo, Shechter, Sharon, McNamara, Stephanie, DuHadaway, James B., Kocher, Olivier N., Brown, Lawrence F., Toker, Alex, Prendergast, George C., Benjamin, Laura E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201498/
https://ncbi.nlm.nih.gov/pubmed/23135917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3055
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