Supplementation with N-3 Long-Chain Polyunsaturated Fatty Acids or Olive Oil in Men and Women with Renal Disease Induces Differential Changes in the DNA Methylation of FADS2 and ELOVL5 in Peripheral Blood Mononuclear Cells

BACKGROUND: Studies in animal models and in cultured cells have shown that fatty acids can induce alterations in the DNA methylation of specific genes. There have been no studies of the effects of fatty acid supplementation on the epigenetic regulation of genes in adult humans. METHODS AND RESULTS:...

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Detalhes bibliográficos
Main Authors: Hoile, Samuel P., Clarke-Harris, Rebecca, Huang, Rae-Chi, Calder, Philip C., Mori, Trevor A., Beilin, Lawrence J., Lillycrop, Karen A., Burdge, Graham C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201459/
https://ncbi.nlm.nih.gov/pubmed/25329159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109896
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