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Drug and xenobiotic biotransformation in the blood–brain barrier: a neglected issue

Drug biotransformation is a crucial mechanism for facilitating the elimination of chemicals from the organism and for decreasing their pharmacological activity. Published evidence suggests that brain drug metabolism may play a role in the development of adverse drug reactions and in the clinical res...

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Detalhes bibliográficos
Main Authors: Agúndez, José A. G., Jiménez-Jiménez, Félix J., Alonso-Navarro, Hortensia, García-Martín, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201098/
https://ncbi.nlm.nih.gov/pubmed/25368552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00335
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