Impact of meriolins, a new class of cyclin-dependent kinase inhibitors, on malignant glioma proliferation and neo-angiogenesis

BACKGROUND: Glioblastomas are the most frequent and most aggressive primary brain tumors in adults. The median overall survival is limited to a few months despite surgery, radiotherapy, and chemotherapy. It is now clearly established that hyperactivity of cyclin-dependent kinases (CDKs) is one of th...

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Detalhes bibliográficos
Main Authors: Jarry, Marie, Lecointre, Céline, Malleval, Céline, Desrues, Laurence, Schouft, Marie-Thérèse, Lejoncour, Vadim, Liger, François, Lyvinec, Gildas, Joseph, Benoît, Loaëc, Nadège, Meijer, Laurent, Honnorat, Jérôme, Gandolfo, Pierrick, Castel, Hélène
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201071/
https://ncbi.nlm.nih.gov/pubmed/24891448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou102
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