Predicting the likelihood of an isocitrate dehydrogenase 1 or 2 mutation in diagnoses of infiltrative glioma

BACKGROUND: Several variables are associated with the likelihood of isocitrate dehydrogenase 1 or 2 (IDH1/2) mutation in gliomas, though no guidelines yet exist for when testing is warranted, especially when an R132H IDH1 immunostain is negative. METHODS: A cohort of 89 patients was used to build ID...

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Main Authors: Chen, Li, Voronovich, Zoya, Clark, Kenneth, Hands, Isaac, Mannas, Jonathan, Walsh, Meggen, Nikiforova, Marina N., Durbin, Eric B., Weiss, Heidi, Horbinski, Craig
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
Assuntos:
Basic and Translational Investigations
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201069/
https://ncbi.nlm.nih.gov/pubmed/24860178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou097
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