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OP01 MISMATCH REPAIR DEFICIENCY CONFERS INCREASED SENSITIVITY TO IONISING RADIATION (XR) IN GLIOBLASTOMA
INTRODUCTION: Combination chemo-radiotherapy, including the alkylating agent temozolomide (TMZ) is standard of care for patients with glioma. Increased TMZ use has lead to sustained interest in the mechanisms underlying acquired resistance. Amongst these, deficiency in mismatch repair (MMR) is best...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4200953/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou251.1 |
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