P64 QUANTITATIVE MGMT METHYLATION ANALYSIS BY PYROSEQUENCING REVEALS A STRONG CORRELATION BETWEEN 1P/19Q CO-DELETION AND HIGH LEVEL METHYLATION IN HIGH GRADE GLIOMAS

INTRODUCTION: Pyrosequencing is a method that allows MGMT methylation to be measured in a quantitative manner. MGMT methylation, along with 1p/19q co-deletion and IDH1 mutation, is an important biomarker in high grade gliomas. MGMT methylation indicates an improved response to temozolomide chemother...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Laxton, R., Doey, L., Aizpurua, M., Bodi, I., King, A., Chandler, C., Bhangoo, R., Beaney, R., Brazil, L., Ashkan, K., Al-Sarraj, S.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200931/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou249.50
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker