P50 DEVELOPING A PHYSIOLOGICALLY RELEVANT BLOOD BRAIN BARRIER MODEL FOR THE STUDY OF DRUG DISPOSITION IN GLIOMA

INTRODUCTION: Many in vitro blood brain barrier (BBB) models have been designed to study the underlying mechanism involved in drug transport across the BBB, but most have not included glioma or cells of human origin. Trans-endothelial electrical resistance (TEER) is a key measure of membrane potenti...

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Main Authors: Kumar, Swati, Shaw, Lisa, Lawrence, Clare, Lea, Robert, Alder, Jane
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
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Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200917/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou249.38
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