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P50 DEVELOPING A PHYSIOLOGICALLY RELEVANT BLOOD BRAIN BARRIER MODEL FOR THE STUDY OF DRUG DISPOSITION IN GLIOMA

INTRODUCTION: Many in vitro blood brain barrier (BBB) models have been designed to study the underlying mechanism involved in drug transport across the BBB, but most have not included glioma or cells of human origin. Trans-endothelial electrical resistance (TEER) is a key measure of membrane potenti...

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Autors principals: Kumar, Swati, Shaw, Lisa, Lawrence, Clare, Lea, Robert, Alder, Jane
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200917/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou249.38
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