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Novel Sustained-Release of Propafenone through Pellets: Preparation and in Vitro/in Vivo Evaluation

In this study, an extrusion-spheronization method was applied successfully to fabricate propafenone hydrochloride (PPF) sustained-release pellets. Using scanning electron microscopy, it was shown that the PPF pellets had a mean size of approximately 950 µm with a spherical shape. The in vitro releas...

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Detalhes bibliográficos
Main Authors: Zhang, Li, Jiang, Ping, Liu, Ji
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200845/
https://ncbi.nlm.nih.gov/pubmed/25184949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150915503
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