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Aging impairs smooth muscle-mediated regulation of aortic stiffness: a defect in shock absorption function?

Increased aortic stiffness is an early and independent biomarker of cardiovascular disease. Here we tested the hypothesis that vascular smooth muscle cells (VSMCs) contribute significantly to aortic stiffness and investigated the mechanisms involved. The relative contributions of VSMCs, focal adhesi...

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Autores principales: Gao, Yuan Z., Saphirstein, Robert J., Yamin, Rina, Suki, Bela, Morgan, Kathleen G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200340/
https://ncbi.nlm.nih.gov/pubmed/25128168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00392.2014
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