Intratracheal administration of cyclooxygenase-1-transduced adipose tissue-derived stem cells ameliorates monocrotaline-induced pulmonary hypertension in rats

The effect of intratracheal administration of cyclooxygenase-1 (COX-1)-modified adipose stem cells (ASCs) on monocrotaline-induced pulmonary hypertension (MCT-PH) was investigated in the rat. The COX-1 gene was cloned from rat intestinal cells, fused with a hemagglutanin (HA) tag, and cloned into a...

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Detalhes bibliográficos
Main Authors: Somanna, Naveen K., Wörner, Philipp M., Murthy, Subramanyam N., Pankey, Edward A., Schächtele, Deborah J., St. Hilaire, Rose-Claire, Jansen, David, Chaffin, Abigail E., Nossaman, Bobby D., Alt, Eckhard U., Kadowitz, Philip J., Izadpanah, Reza
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Integrative Cardiovascular Physiology and Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200339/
https://ncbi.nlm.nih.gov/pubmed/25320332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00589.2013
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