Vascular dysfunction precedes hypertension associated with a blood pressure locus on rat chromosome 12

We previously isolated a 6.1-Mb region of SS/Mcwi (Dahl salt-sensitive) rat chromosome 12 (13.4–19.5 Mb) that significantly elevated blood pressure (BP) (Δ+34 mmHg, P < 0.001) compared with the SS-12(BN) consomic control. In the present study, we examined the role of vascular dysfunction and remo...

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Detalhes bibliográficos
Main Authors: Prisco, Sasha Z., Priestley, Jessica R. C., Weinberg, Brian D., Prisco, Anthony R., Hoffman, Matthew J., Jacob, Howard J., Flister, Michael J., Lombard, Julian H., Lazar, Jozef
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Vascular Biology and Microcirculation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200336/
https://ncbi.nlm.nih.gov/pubmed/25320330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00464.2014
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