Unexpected maturation of PI3K and MAPK-ERK signaling in fetal ovine cardiomyocytes

In the first two-thirds of gestation, ovine fetal cardiomyocytes undergo mitosis to increase cardiac mass and accommodate fetal growth. Thereafter, some myocytes continue to proliferate while others mature and terminally differentiate into binucleated cells. At term (145 days gestational age; dGA) a...

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Bibliographic Details
Main Authors: Chattergoon, N. N., Louey, S., Stork, P. J., Giraud, G. D., Thornburg, K. L.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2014
Subjects:
Integrative Cardiovascular Physiology and Pathophysiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200334/
https://ncbi.nlm.nih.gov/pubmed/25128174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00833.2013
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