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Constitutive activation of CaMKKα signaling is sufficient but not necessary for mTORC1 activation and growth in mouse skeletal muscle

Skeletal muscle loading/overload stimulates the Ca(2+)-activated, serine/threonine kinase Ca(2+)/calmodulin-dependent protein kinase kinase-α (CaMKKα); yet to date, no studies have examined whether CaMKKα regulates muscle growth. The purpose of this study was to determine if constitutive activation...

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Hlavní autoři: Ferey, Jeremie L. A., Brault, Jeffrey J., Smith, Cheryl A. S., Witczak, Carol A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200303/
https://ncbi.nlm.nih.gov/pubmed/25159322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00322.2014
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