Constitutively Active CaMKKα Stimulates Skeletal Muscle Glucose Uptake in Insulin-Resistant Mice In Vivo

In insulin-sensitive skeletal muscle, the expression of constitutively active Ca(2+)/calmodulin-dependent protein kinase kinase α (caCaMKKα) stimulates glucose uptake independent of insulin signaling (i.e., Akt and Akt-dependent TBC1D1/TBC1D4 phosphorylation). Our objectives were to determine whethe...

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Detalhes bibliográficos
Main Authors: Hinkley, J. Matthew, Ferey, Jeremie L., Brault, Jeffrey J., Smith, Cheryl A.S., Gilliam, Laura A.A., Witczak, Carol A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2014
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868053/
https://ncbi.nlm.nih.gov/pubmed/24101676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0452
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