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Collecting duct-specific knockout of renin attenuates angiotensin II-induced hypertension
The physiological and pathophysiological significance of collecting duct (CD)-derived renin, particularly as it relates to blood pressure (BP) regulation, is unknown. To address this question, we generated CD-specific renin knockout (KO) mice and examined BP and renal salt and water excretion. Mice...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4200300/ https://ncbi.nlm.nih.gov/pubmed/25122048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00367.2014 |
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