Essential Role of Protein-tyrosine Phosphatase 1B in the Modulation of Insulin Signaling by Acetaminophen in Hepatocytes

Many drugs are associated with the development of glucose intolerance or deterioration in glycemic control in patients with pre-existing diabetes. We have evaluated the cross-talk between signaling pathways activated by acetaminophen (APAP) and insulin signaling in hepatocytes with or without expres...

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Главные авторы: Mobasher, Maysa Ahmed, de Toro-Martín, Juan, González-Rodríguez, Águeda, Ramos, Sonia, Letzig, Lynda G., James, Laura P., Muntané, Jordi, Álvarez, Carmen, Valverde, Ángela M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2014
Предметы:
Signal Transduction
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200289/
https://ncbi.nlm.nih.gov/pubmed/25204659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.539189
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