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Protein-tyrosine Phosphatases Are Involved in Interferon Resistance Associated with Insulin Resistance in HepG2 Cells and Obese Mice

Insulin resistance is a risk factor for non-response to interferon/ribavirin therapy in patients with chronic hepatitis C. The aim of this study was to determine the role played by protein-tyrosine phosphatases (PTPs) in the absence of interferon-α (IFNα) response associated with insulin resistance....

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Bibliographische Detailangaben
Hauptverfasser: García-Ruiz, Inmaculada, Solís-Muñoz, Pablo, Gómez-Izquierdo, Érica, Muñoz-Yagüe, María Teresa, Valverde, Ángela M., Solís-Herruzo, José A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365992/
https://ncbi.nlm.nih.gov/pubmed/22493491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.342709
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