Leigh Syndrome in Drosophila melanogaster: MORPHOLOGICAL AND BIOCHEMICAL CHARACTERIZATION OF Surf1 POST-TRANSCRIPTIONAL SILENCING

Leigh Syndrome (LS) is the most common early-onset, progressive mitochondrial encephalopathy usually leading to early death. The single most prevalent cause of LS is occurrence of mutations in the SURF1 gene, and LS(Surf1) patients show a ubiquitous and specific decrease in the activity of mitochond...

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Detalhes bibliográficos
Main Authors: Da-Rè, Caterina, von Stockum, Sophia, Biscontin, Alberto, Millino, Caterina, Cisotto, Paola, Zordan, Mauro A., Zeviani, Massimo, Bernardi, Paolo, De Pittà, Cristiano, Costa, Rodolfo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Bioenergetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200275/
https://ncbi.nlm.nih.gov/pubmed/25164807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.602938
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