Post-transcriptional Silencing and Functional Characterization of the Drosophila melanogaster Homolog of Human Surf1

Mutations in Surf1, a human gene involved in the assembly of cytochrome c oxidase (COX), cause Leigh syndrome, the most common infantile mitochondrial encephalopathy, characterized by a specific COX deficiency. We report the generation and characterization of functional knockdown (KD) lines for Surf...

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Bibliografiske detaljer
Main Authors: Zordan, Mauro A., Cisotto, Paola, Benna, Clara, Agostino, Alessandro, Rizzo, Giorgia, Piccin, Alberto, Pegoraro, Mirko, Sandrelli, Federica, Perini, Giuliana, Tognon, Giuseppe, De Caro, Raffaele, Peron, Samantha, Kronniè, Truus te, Megighian, Aram, Reggiani, Carlo, Zeviani, Massimo, Costa, Rodolfo
Format: Artigo
Sprog:Inglês
Udgivet: Copyright © 2006 by the Genetics Society of America 2006
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Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456150/
https://ncbi.nlm.nih.gov/pubmed/16172499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.049072
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