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Critical Roles of Interdomain Interactions for Modulatory ATP Binding to Sarcoplasmic Reticulum Ca(2+)-ATPase

ATP has dual roles in the reaction cycle of sarcoplasmic reticulum Ca(2+)-ATPase. Upon binding to the Ca(2)E1 state, ATP phosphorylates the enzyme, and by binding to other conformational states in a non-phosphorylating modulatory mode ATP stimulates the dephosphorylation and other partial reaction s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Clausen, Johannes D., Holdensen, Anne Nyholm, Andersen, Jens Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200266/
https://ncbi.nlm.nih.gov/pubmed/25193668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.571687
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