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The Length of the A-M3 Linker Is a Crucial Determinant of the Rate of the Ca(2+) Transport Cycle of Sarcoplasmic Reticulum Ca(2+)-ATPase

Ion translocation by the sarcoplasmic reticulum Ca(2+)-ATPase depends on large movements of the A-domain, but the driving forces have yet to be defined. The A-domain is connected to the ion-binding membranous part of the protein through linker regions. We have determined the functional consequences...

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Detalhes bibliográficos
Main Authors: Holdensen, Anne Nyholm, Andersen, Jens Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673294/
https://ncbi.nlm.nih.gov/pubmed/19278994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900977200
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