Post-translational Regulation of Mitogen-activated Protein Kinase Phosphatase (MKP)-1 and MKP-2 in Macrophages Following Lipopolysaccharide Stimulation: THE ROLE OF THE C TERMINI OF THE PHOSPHATASES IN DETERMINING THEIR STABILITY

MAPK phosphatases (MKPs) are critical modulators of the innate immune response, and yet the mechanisms regulating their accumulation remain poorly understood. In the present studies, we investigated the role of post-translational modification in the accumulation of MKP-1 and MKP-2 in macrophages fol...

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Detalles Bibliográficos
Main Authors: Crowell, Sara, Wancket, Lyn M., Shakibi, Yasmine, Xu, Pingping, Xue, Jianjing, Samavati, Lobelia, Nelin, Leif D., Liu, Yusen
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200237/
https://ncbi.nlm.nih.gov/pubmed/25204653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.591925
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