The roles of mitoferrin-2 in the process of arsenic trioxide-induced cell damage in human gliomas

BACKGROUND: Among glioma treatment strategies, arsenic trioxide (As(2)O(3)) has shown efficacy as a therapeutic agent against human gliomas. However, the exact antitumor mechanism of action of As(2)O(3) is still unclear. Mitochondria are considered to be the major source of intracellular reactive ox...

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Bibliografiske detaljer
Main Authors: Wang, Chunlei, Chen, Xiaofeng, Zou, Huichao, Chen, Xin, Liu, Yaohua, Zhao, Shiguang
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200193/
https://ncbi.nlm.nih.gov/pubmed/25256833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40001-014-0049-5
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