In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells

BACKGROUND: The increasing usage of statins (the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors) has revealed a number of unexpected beneficial effects, including a reduction in cancer risk. METHODS: We investigated the direct anticancer effects of different statins approved for clinical...

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Detalhes bibliográficos
Main Authors: Jiang, P, Mukthavaram, R, Chao, Y, Nomura, N, Bharati, I S, Fogal, V, Pastorino, S, Teng, D, Cong, X, Pingle, S C, Kapoor, S, Shetty, K, Aggrawal, A, Vali, S, Abbasi, T, Chien, S, Kesari, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200085/
https://ncbi.nlm.nih.gov/pubmed/25093497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.431
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