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MicroRNA-155 Deficient Mice Experience Heightened Kidney Toxicity When Dosed with Cisplatin

The development of nephrotoxicity limits the maximum achievable dosage and treatment intervals for cisplatin chemotherapy. Therefore, identifying mechanisms that regulate this toxicity could offer novel methods to optimize cisplatin delivery. MicroRNAs are capable of regulating many different genes,...

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Autores principales: Pellegrini, Kathryn L., Han, Tao, Bijol, Vanesa, Saikumar, Janani, Craciun, Florin L., Chen, William W., Fuscoe, James C., Vaidya, Vishal S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
Materias:
120
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200048/
https://ncbi.nlm.nih.gov/pubmed/25015656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu143
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