MicroRNA-155 Deficient Mice Experience Heightened Kidney Toxicity When Dosed with Cisplatin

The development of nephrotoxicity limits the maximum achievable dosage and treatment intervals for cisplatin chemotherapy. Therefore, identifying mechanisms that regulate this toxicity could offer novel methods to optimize cisplatin delivery. MicroRNAs are capable of regulating many different genes,...

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Hlavní autoři: Pellegrini, Kathryn L., Han, Tao, Bijol, Vanesa, Saikumar, Janani, Craciun, Florin L., Chen, William W., Fuscoe, James C., Vaidya, Vishal S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
120
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200048/
https://ncbi.nlm.nih.gov/pubmed/25015656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu143
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