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Pharmacological and genetic depletion of fibrinogen protects from kidney fibrosis

Fibrinogen (Fg) has been implicated in the pathogenesis of several fibrotic disorders by acting as a profibrotic ligand for a variety of cellular surface receptors and by modulating the provisional fibrin matrix formed after injury. We demonstrated increased renal Fg expression after unilateral uret...

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Bibliografiska uppgifter
Huvudupphovsmän: Craciun, Florin L., Ajay, Amrendra K., Hoffmann, Dana, Saikumar, Janani, Fabian, Steven L., Bijol, Vanesa, Humphreys, Benjamin D., Vaidya, Vishal S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137131/
https://ncbi.nlm.nih.gov/pubmed/25007874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00189.2014
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