Topical pimecrolimus inhibits high-dose UVB irradiation-induced epidermal Langerhans cell migration, via regulation of TNF-α and E-cadherin

BACKGROUND: Topical pimecrolimus has been shown to reverse epidermal CD1a(+) Langerhans cell reduction induced by high-dose ultraviolet (UV)B irradiation, but the mechanism is still unclear. This study aimed to investigate the possible mechanism of the effect of pimecrolimus on high-dose UVB-irradia...

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Autori principali: Yin, ZhiQiang, Xu, JiaLi, Zhou, BingRong, Wu, Di, Xu, Yang, Zhang, JiaAn, Luo, Dan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2014
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199986/
https://ncbi.nlm.nih.gov/pubmed/25336924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S70790
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