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Evaluation of the pharmacokinetic and pharmacodynamic drug interactions between cilnidipine and valsartan, in healthy volunteers

PURPOSE: Although cilnidipine and valsartan are widely coadministered to patients with hypertension, their drug–drug interaction potential has not been investigated. This study compared the pharmacokinetic (PK), pharmacodynamic (PD), and tolerability profiles of cilnidipine and valsartan, both alone...

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Autors principals: Lee, Jieon, Lee, Howard, Jang, Kyungho, Lim, Kyoung Soo, Shin, Dongseong, Yu, Kyung-Sang
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199974/
https://ncbi.nlm.nih.gov/pubmed/25336921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S68574
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