Evaluation of the pharmacokinetic and pharmacodynamic drug interactions between cilnidipine and valsartan, in healthy volunteers

PURPOSE: Although cilnidipine and valsartan are widely coadministered to patients with hypertension, their drug–drug interaction potential has not been investigated. This study compared the pharmacokinetic (PK), pharmacodynamic (PD), and tolerability profiles of cilnidipine and valsartan, both alone...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Lee, Jieon, Lee, Howard, Jang, Kyungho, Lim, Kyoung Soo, Shin, Dongseong, Yu, Kyung-Sang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2014
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199974/
https://ncbi.nlm.nih.gov/pubmed/25336921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S68574
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