Fusion of cell-penetrating peptides to thermally responsive biopolymer improves tumor accumulation of p21 peptide in a mouse model of pancreatic cancer

Current therapies for the treatment of pancreatic cancer are limited. The limitations of this type of treatment are abundant. The majority of chemotherapeutic agents used in clinics are highly toxic to both tumor cells and normal tissues due to the lack of specificity. Resistance can develop due to...

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Hlavní autoři: Walker, Leslie R, Ryu, Jung Su, Perkins, Eddie, McNally, Lacey R, Raucher, Drazen
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2014
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199967/
https://ncbi.nlm.nih.gov/pubmed/25336913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S60451
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