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Fusion of cell-penetrating peptides to thermally responsive biopolymer improves tumor accumulation of p21 peptide in a mouse model of pancreatic cancer

Current therapies for the treatment of pancreatic cancer are limited. The limitations of this type of treatment are abundant. The majority of chemotherapeutic agents used in clinics are highly toxic to both tumor cells and normal tissues due to the lack of specificity. Resistance can develop due to...

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Bibliografiske detaljer
Main Authors: Walker, Leslie R, Ryu, Jung Su, Perkins, Eddie, McNally, Lacey R, Raucher, Drazen
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199967/
https://ncbi.nlm.nih.gov/pubmed/25336913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S60451
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