HMGB1 enhances immune suppression by facilitating the differentiation and suppressive activity of myeloid-derived suppressor cells

Chronic inflammation often precedes malignant transformation and later drives tumor progression. Likewise, subversion of the immune system plays a role in tumor progression, with tumoral immune escape now well recognized as a crucial hallmark of cancer. Myeloid-derived suppressor cells (MDSC) are el...

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Bibliografiske detaljer
Main Authors: Parker, Katherine, Sinha, Pratima, Horn, Lucas A., Clements, Virginia K., Yang, Huan, Li, Jianhua, Tracey, Kevin J., Ostrand-Rosenberg, Suzanne
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199911/
https://ncbi.nlm.nih.gov/pubmed/25164013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2347
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